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Validation platform for ultrasound-based monitoring of thermal ablation

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Pompeu-Robinson, A. M., Gray, J., Marble, J., Peikari, H., Hall, J., U-Thainual, P., Aboofazeli, M., Lasso, A., & Fichtinger, G. (2010). Validation platform for ultrasound-based monitoring of thermal ablation. Proceedings Volume 7625, Medical Imaging 2010: Visualization, Image-Guided Procedures, and Modeling, 7625, 76250T. https://doi.org/10.1117/12.844053

Description

Details
Author(s)

Pompeu-Robinson, Alexandra M.
Gray, James
Marble, Joshua
Peikari, Hamed
Hall, Jena
U-Thainual, Paweena
Aboofazeli, Mohammad
Lasso, Andras
Fichtinger, Gabor

Title

Validation platform for ultrasound-based monitoring of thermal ablation

Publication Type

article

Date issued

2010

Journal/Book/Host Title

Proceedings Volume 7625, Medical Imaging 2010: Visualization, Image-Guided Procedures, and Modeling

Volume

7625

Start Page

76250T

Abstract

PURPOSE: A ground-truth validation platform was developed to provide spatial correlation between ultrasound (US), temperature measurements and histopathology images to validate US based thermal ablation monitoring methods.

METHOD: The test-bed apparatus consists of a container box with integrated fiducial lines. Tissue samples are suspended within the box using agar gel as the fixation medium. Following US imaging, the gel block is sliced and pathology images are acquired. Interactive software segments the fiducials as well as structures of interest in the pathology and US images. The software reconstructs the regions in 3D space and performs analysis and comparison of the features identified from both imaging modalities.

RESULTS: The apparatus and software were constructed to meet technical requirements. Tissue samples were contoured, reconstructed and registered in the common coordinate system of fiducials. There was agreement between the sample shapes, but systematic shift of several millimeters was found between histopathology and US. This indicates that during pathology slicing shear forces tend to dislocate the fiducial lines. Softer fiducial lines and harder gel material can eliminate this problem.

CONCLUSION: Viability of concept was presented. Despite our straightforward approach, further experimental work is required to optimize all materials and customize software. [ABSTRACT FROM AUTHOR]

DOI

10.1117/12.844053

ISSN

0277-786X

Publication note

Final article published

Publisher

Society of Photo-optical Instrumentation Engineers (SPIE)

Peer reviewed?

Peer reviewed

Use rights

http://rightsstatements.org/vocab/InC-EDU/1.0/
©2010. SPIE.